#04026: De novo Peptide Sequencing Using a Covalent Derivatization Strategy
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TECH FIELD(S)
Research Tool
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FEATURES
The invention describes a dual labeling strategy that enhances the mass spectrometry analysis of peptides. A de novo sequencing method is described that utilizes both guanidination of lysine residues in conjunction with amidination of the N-termini of peptides to be analyzed by mass spectrometry.
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BENEFITS
- The invention facilitates identification of N- and C-terminal fragment ions.
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INVENTOR(S)
James P. Reilly and Richard L. Beardsley
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INTELLECTUAL PROPERTY STATUS
US patent application pending.
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CONTACT INFORMATION
For additional information on this technology, please contact Bill Brizzard, Director of Technology Transfer , IURTC:
Indiana University Research & Technology Corporation
501 North Morton Street, Suite 204
Bloomington, IN 47404
Telephone:812-855-3597
bbrizzar@iu.edu
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