#07163: GLUT-1 polyclonal antibody
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TECH FIELD(S)
Research Tool
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FEATURES
The mammalian GLUT genes belong to a large superfamily of genes whose protein products are involved in the transport of a variety of hexoses and other carbon compounds. Recent biochemical studies identified the glucose transporter protein GLUT-1 as a receptor for HTLV-1 and HTLV-2.
Glut-1: Glucose transporter, specific for extracellular loop 1 (ECL1)
Antibody raised to a GLUT-1 ECL1 synthetic peptide
Specificity: human
Host: chicken
Type: polyclonal, IgY
Ref: Virology 349:184-196
Infection of CD4+ T lymphocytes by the human T cell leukemia virus type 1 is mediated by the glucose transporter...
Jin, Q. , Agrawal, L. , VanHorn-Ali, Z. , Alkhatib, G., May 2006
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BENEFITS
This is the first antibody published that specifically detects cell surface GLUT-1. This antibody inhibits HTLV-1 fusion and infection in mammalian cell lines.
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INVENTOR(S)
Ghalib Alkhatib, Ph.D.
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INTELLECTUAL PROPERTY STATUS
Non-patented research tool
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CONTACT INFORMATION
For additional information on this technology, please contact Rebecca Lyon, Ph.D., Associate Director of Life Sciences, IURTC:
Indiana University Research & Technology Corporation
351 West 10th Street
Indianapolis, IN 46202
Telephone: 317.278.1916
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